Automated Live Cell Imaging

The CellAssist 50

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A Researcher's Insight

Automated Time Series Imaging of 50 Incubated Plates 24/7

  • The CellAssist 50 is an automated time series cell imaging system with an integrated 50-plate CO2 incubator enabling deep insights into cell and tissue dynamics.

  • The CellAssist Software, the foundation of the cell, and tissue visualization and analysis capabilities, automatically builds a database of images, and metrics including growth rate, confluence, colony counts, and sizes.

  • Up to 50 incubated cell culture plates, each with separate imaging schedules, allow for consistently timed around-the-clock experiments.
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Improve Reproducibility, and Accuracy of Your Cell Culture Experiments:

  • Automate Your Time Series Imaging:
    Remotely schedule, execute, and capture time series images of incubated plates at your desired frequency 24/7
  • Increase Productivity:
    Maximize throughput, and capture comprehensive data from up to 50 plates with 100’s of stacks of images per plate
  • Protect User, and Cell Health:
    Robotics enable the automatic loading and unloading of plates without disrupting the incubator’s cell culture environment
  • Image Cells, and Tissues:
    Image adherent cells, suspension cells, and tissues with 1,000’s of images/scan using 100+ focal planes, 2 µm to 50 µm apart (user selected)

Time Series Imaging of up to 50 Plates at up to 100 Focal Planes

  • Phase contrast & bright-field; 4x, 10x, and 20x
  • 50 plates, and 100+ focal planes, 2 µm to 50 µm apart (user selected)
  • Superb image registration across scans
  • 6-well through 384-well flat bottom and round bottom cell culture plates
  • Temperature, CO2, and humidity controls
  • 2.5GB to 40GB+ of images, and data per scan

CellAssist 50’s Robust Workflow

Unprecedented Efficiency, and Automation

1

Captures methods, and
materials to initiate
project through
barcode scanner

2

The fully
automated plate
mover transports,
and inserts plate for
imaging

3

Acquires, views, and
transmit images to
CellAssist Analysis
Workstation

4

The plate mover
removes plate back to
the storage rack for
continued workflow

5

CellAssist Analysis
Workstation
analyzes,
compares, and
reports images

Take Your Live Cell Imaging to Many Levels:

Capture up to 30,000 images at 100+ focal planes,
each 2 μm to 50 μm apart, with automated handling
of culture plates, and barcode scanning

Image all the cells in all the wells including at the periphery, and calculate both inner- and outer-well confluency

5-megapixel cameras collect images at 4x, and 10x with
phase contrast, and bright-field, that rival the
resolution, and quality taken at (20x, and 40x) on other
instruments

Time-stamped barcode activity logs, and setup condition tools eliminate mislabeling, and crosscontamination

Multiple cameras generate 1,000’s of high resolution image sets of 2.5GB to 40GB+ per scan in minutes

z-stacks-focal-planes-live-cell-imaging

Integrated Solution Protects Your Team and Cell Health:

  • Built-in incubator eliminates time at the inverted microscope enabling the researcher to focus on interpretation data

  • Robotic handling of plates protects cells, and lab personnel

  • Once seeded, and inserted, plate images are automatically captured without user intervention

  • Image an entire plate in less than 10 minutes without disrupting the cell culture environment

The CellAssist Software:

  • A centralized location for storing, and archiving your captured data

  • Remotely view your captured data

  • Generate informed quantitative reports on cell confluency, cell growth, scratch gap area recolonization, and viral plaque counts