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The CellAssist

The New CellAssist:

Thrive Bioscience’s new benchtop instrument, the CellAssist, automatically builds a database of images, metrics, and methods and materials to ensure centralized capture and retention of data. The unique CellAssist is setting new standards for reproducible adherent cell culture in numerous laboratory applications.

The CellAssist replaces your time at the inverted microscope to acquire, organize, and analyze images of all your cells in SBS format plates. Minutes after inserting a standard 6-well through 96-well plate into the CellAssist, the system captures, displays and processes hundreds of high-resolution images of adherent cells at 4x or 10x, using phase contrast or bright-field imaging. With barcodes to identify plates and reagents, the CellAssist maintains a complete centralized record of growth and behavior of all cells.

EvalCore Analysis Workstation

Thrive Bioscience’s EvalCore is a computer workstation at the heart of the CellAssist’s visualization and analysis capabilities. It can be placed in the laboratory or office to automatically download all of the images from the CellAssist instrument. 

The CellReporter software analyzes the images, and presents a comprehensive and coherent view into all of the images and metrics from the entire history of all of the laboratory’s projects.

In addition, the entire plate setup information, normally entered into the CellAssist tablet, can also be entered into EvalCore and automatically transmitted to the CellAssist instrument.

CellAssist Features and Specifications

The CellAssist provides image capture, reports, and a database on adherent cells with these added features and product specifications:

Instrumentation

  • Barcode tracking of culture plates, reagents and workflow 
  • Imaging of adherent cells in standard 6-well through 96-well plates
  • Scanning modes include full-well, center-of-well and regions of interest
  • Wireless and wired network connection between CellAssist instrument(s) and EvalCore Analysis Workstation, enabling location installation flexibility

Software

  • Central database of images and metrics, including growth rates, confluence, colony count and size, and monoclonality
  • Detailed viewing of stitched images at varying z-height depths along with zoom, measurement, and export capabilities 
  • Time lapse viewing capability to visualize colony formation, morphology, differentiation, and monoclonality

  • Microscopy: 4x phase contrast, 4x bright-field, 10x phase contrast, 10x bright-field (modes supported are plate type dependent)
  • Resolution: 2.1 μm/pixel at 4x; 0.84 μm/pixel at 10x
  • Image registration: +/- 15 μm between scans (after removing and reloading plate)
  • User interfaces: Tablet in laboratory and EvalCore Analysis Workstation in laboratory or office

  • Accessories Included with CellAssist:
    • Barcode reader (Bluetooth) for plate ID, reagents and experiment data entry
    • Tablet user interface (Wi-Fi) in laboratory for viewing and project planning
    • Wireless access point for private network with EvalCore Analysis Workstation

  • Physical:
    • Internal temperature: 37°C
    • Local storage: 4 TB
    • Dimensions: 0.5m x 0.5m x 0.6m (lwh) / Weight: 26 kg
    • Operating environment: temperature 20-27C; relative humidity 20-80%
    • Power requirements: 100-240VAC 50/60Hz; 650W max

  • Powerful computing workstation combined with CellReporter and CA Control software for image analysis and project management
  • Networked to the CellAssist with either a wired or wireless connection
  • Automatic image transfer from CellAssist instrument(s)
  • Image and video export formats: png, mp4
  • Physical:
    • Local storage: 18TB
    • Dimensions: 0.5m x 0.2m x 0.8m (lwh) (without monitor) / Weight: 10 kg
    • Power requirements: 100-240VAC, 50/60Hz; 890W max
    •  





Specifications are subject to change without notice. The CellAssist is for in vitro and laboratory use only.

The CellAssist Experience

Learn more about the CellAssist and its capabilities with this video. 

CellAssist Workflow

Capture methods
and materials

Insert plate into
CellAssist for imaging

Capture, view and
transmit to database

Remove plate for
continued workflow

Analyze, compare, and share Images

CellAssist Benefits For Your Laboratory

Centralized database provides consistent and shareable images 
to improve your cell culture experiments and results

  • Organizes images across time, cell lines, and labs
  • Images and displays cells at the same location on the cell culture plate within 15 μm across scans
  • Generates extensive data sets of over 3 GB of images per scan

Objective metrics and quantitative reports
enhance cell culture decision 
making and productivity

  • Characterizes cell dynamics, including growth curves, confluence, and the number and area of colonies
  • Analyzes and compares cells to support decision-making to reduce variability and increase quality
  • Allows comparison and optimization of multiple methods and materials

Key workflow details and status of cells are captured and archived 
to provide confidence that data is not lost or compromised

  • Accurately records and time-stamps your cell culture process with a barcode scanner
  • Captures and archives the key workflow details and the status of cells to provide confidence that data is not lost or compromised
  • Enables comparison with previous experiments to optimize and ensure reproducibility of your cell culture